While walking home from her office job, Kaoru Nagase is approached by a man dressed all in white who apologizes for a mistake that led to her early death. To make up for this mistake, he vows to let her reincarnate into another world.
Introducing her to Celestine, the goddess for her new world, the goddess reforms Kaoru’s body and grants her a few requests for her new life. Alongside now being a young woman again, Kaoru asks for a box with infinite storage space as well as the ability to make any potion she can think of.
Starting off her new life in a medieval world, Kaoru realizes that there isn’t much magic in the world, which causes her magnificent abilities to make her the frequent target of greedy nobles. However, using the cunning she honed from before her death, Kaoru does her best to help those that need helping and avoid becoming anyone’s tool.
You don’t have to have magnificent art or even an innovative plot if you just make it fun. I feel like that is the wheelhouse of this series, and it does work. If you are looking for more anime recommendations like I Shall Survive Using Potions, head on down below.
Anime Like I Shall Survive Using Potions!
For Fans of Independent Women That Wish to Remain Independent
Saving 80,000 Gold in Another World for My Retirement
After accidentally falling off a cliff, Mitsuha wakes up in a fantasy land.
Upon saving a girl from a wolf attack, she discovers that she didn’t die in her previous life, but rather accidentally ripped away a piece of a God’s power that lets her transport herself between that world and modern Japan.
With this magnificent power, she decides to take items from modern Japan to sell in the fantasy world. She has calculated that making 80,000 gold in the fantasy land will be enough to retire if she were to get trapped in either world forever.
Now begins her money-making schemes!
Of all the other anime recommendations, Saving 80,000 Gold in Another World provides the most similar experience to I Shall Survive Using Potions. Take out the potions, and they would be near indistinguishable.
Both series are both about women who end up in a fantasy world. They then use their unique ability to fund a life for themselves all while helping those around them. Both are strongly independent women that neither wish to be shackled to nobility nor do they want to immediately get married and settle down. Instead, they focus on their businesses and use tremendous cunning to manipulate things to go the way they want.
Didn’t I Say to Make My Abilities Average in the Next Life?!
Because of her exceptional abilities, Misato Kurihara never got to live a normal life. However, after her sudden death, she is offered reincarnation and one wish. Her wish is to have average abilities so that she can live an average life.
Unfortunately, reincarnated as a noble’s daughter, she still has impressive magic ability.
Determined to still have her normal life, she flees to a far away hunter school and attempts to hide her abilities.
Both I Shall Survive Using Potions and Didn’t I Say to Make My Abilities Average in the Next Life are female-led isekai that poke fun at the concept that an overpowered main character would have trouble living a pleasant life.
While I Shall Survive Using Potions is about avoiding being chained down by nobility that would use them up like a cash cow, Didn’t I Say to Make My Abilities Average in the Next Life is about trying to hide OP magic so she can have friends that treat her like a normal person.
Both series are pretty focused on slice of life activities, but Didn’t I Say to Make My Abilities Average in the Next Life is definitely a Cute Girls Doing Cute Things anime with a bit more action. However, as she is overpowered, that action is often over quickly.
I’ve Been Killing Slimes for 300 Years and Maxed Out My Level
Dying from overwork, Azusa Aizawa is allowed to reincarnate into a new world as a witch that will live forever.
Wanting to never be overworked again, she leisurely kills slimes in order to pay for living expenses. However, this meager amount of XP stacks over 300 years of doing it, and she finds herself at max level.
Fearing someone will try to thrust work upon her, she decides to try and hide her strength.
While I Shall Survive Using Potions is about making potions to fit the needs of the time and living life, I’ve Been Killing Slimes for 300 Years is solely focused on living life and dodging every attempt to have adventure foisted upon her.
Both I Shall Survive Using Potions and I’ve Been Killing Slimes for 300 Years are female-led isekai anime about main characters that just want to live a pleasant, happy life on her own with friends and not have a huge amount of responsibility on their shoulders.
While both series are really about a woman forging friendships with a variety of people, I’ve Been Killing Slimes for 300 Years becomes a Cute Girls Doing Cute Things series since it really only has female characters.
Ascendance of a Bookworm
Motosu Urano loves books. She recently got her librarian certification and was about to enter her dream job when an earthquake caused her to be crushed by her collection of books.
She is reincarnated into a new world as the five year old daughter of a soldier. Unfortunately, in this world, books are reserved for the elite nobility.
What do you do when your station in life does not afford you access to books? Make your own.
Both I Shall Survive Using Potions and Ascendance of a Bookworm are about women reincarnated in a fantasy world as a younger woman who is dripping with passion for a specific topic.
Ascendance of a Bookworm has the main character in a new body, but with the same passion for books she had in her old life. This is in contrast to I Shall Survive Using Potions where Kaoru is just a younger version of herself in a new world.
While I Shall Survive Using Potions is potion-focused, Ascendance of a Bookworm is focused on making books and the process of doing so. Myne doesn’t have any special powers, so it is an isekai more grounded in realism, but just as pleasant to watch.
For Fans of Making Potions
Management of a Novice Alchemist
After her parent’s death, young Sarasa was inspired to become an alchemist and graduated from the Royal Alchemist Academy.
Sacrificing friendships for hard work, she graduates with top marks and under the apprenticeship of a master alchemist.
This master helps her get set up with her first alchemy shop. It is in the middle of nowhere, but surrounded by top-notch alchemy ingredients.
While starting up a new shop is hard work, Sarasa is no stranger to working hard for her dreams.
If you like I Shall Survive Using Potions because it was about a potion-maker, Management of an Alchemist is also about a girl who makes potions, but does so in a more realistic way. Kaoru thinks of a potion and it appears. Management of an Alchemist has her need to gather ingredients and do the proper ritual to brew it.
While both are potion-focused in different ways, both series provide a similarly “cute” experience. I Shall Survive Using Potions has a number of male characters, and doesn’t come off as much of a Cute Girls Doing Cute Things experience despite even the adults looking like children. Management of an Alchemist, however, is predominately cute anime girls and does enjoy some CGDCT slice of work life elements.
Cheat Pharmacist’s Slow Life – Making a Drugstore in Another World
Formerly a corporate slave, Reiji was transported to another world. Using his skills, he started making potions that were effective, and most importantly, didn’t taste like absolute garbage.
Now, Reiji lives a slow life on the outskirts of a village by making potions and running a pharmacy.
Both I Shall Survive Using Potions and Drugstore in Another World are about main characters that sling potions for a living. Both series feature isekai’d main characters whose special skill in their new world is brewing said potions. However, Drugstore in Another World is fully medicine-focused.
While both series are about making potions for people, Drugstore in Another World does have some key differences. It has a male main character and a wholesome, but strong harem vibe. It is also more focused on slice of life comedy rather than just pleasant slice of life living like I Shall Survive Using Potions.
The Saint’s Magic Power is Omnipotent
Sei, a young office worker, is summoned to a new world. However, the people who summoned her to banish dark magic from the world only meant to summon one person they would call Saint. Instead, they summoned two, and Sei discovers that they actually like the other girl better.
Not really caring about that, she ends up making potions at a research institute using her newfound magic. Unfortunately, while she is unexpectedly talented at her work and happy doing it, she begins to think that she is indeed the Saint.
Both I Shall Survive Using Potions and The Saint’s Magic Power is Omnipotent are about adult office ladies isekai’d to another world where they become a potion-maker to help people. You get to enjoy a mature main character follow their passion in a pleasant low-action adventure.
The big difference between these two is more the tone. I Shall Survive Using Potions is designed to be cute and relaxing slice of life. Alternatively, The Saint’s Magic Power is Omnipotent grows a deeper plot as its goes on, has a romantic element, and it fleshes out a core cast of characters. In essence, The Saint’s Magic Power is Omnipotent is for people that liked the potion-making aspect of I Shall Survive Using Potions, but did want a more plot-focused isekai experience rather than a slice of life one.
For Fans of Helping People With Medicine
Parallel World Pharmacy
After dedicating himself to creating medicines as a pharmacist, Kani Yakutani works himself to death at the age of 31.
He awakens in the form of a ten-year-old boy that has been struck by lightning. He discovers that he is the son of a prestigious family as well the host to the guardian deity of medicine. This allows him to immediately diagnose illnesses in others.
While this is a miraculous ability, he discovers the state of medicine in this world is primitive and takes up his previous profession from his past life as a pharmacist once again.
While I Shall Survive Using Potions isn’t only about making potions to be used as medicine, it is a large focus. Alternatively, Parallel World Pharmacy isn’t only using potions as medicine, but is exploring other medicinal magic and techniques as well.
Essentially, if you like nice main characters healing sick people and not being used as tools for the elite class, I Shall Survive Using Potions and Parallel World Pharmacy share that. It is just that Parallel World Pharmacy is fully focused on a medicine-based plot whereas I Shall Survive Using Potions has many other slice of life adventures.
The Great Cleric
After suddenly dying, a salaryman wakes to find himself in another world and in the body of a young teen. Taking up the name of Luciel, he decides to become a healer in order to help people and lead a peaceful life.
Discovering the world is incredibly dangerous, Luciel heads to the Adventurers Guild to try and train his body so he won’t immediately be killed on the road. There, he discovers that healers have a rather poor reputation among adventurers for charging prices so high that adventurers either die due to not being able to afford treatment or trade their life for being sold into slavery.
Working at the Adventurers Guild in return for martial training, Luciel offers his healing skills to wounded adventurers and hopes to someday right the corrupt system.
Like making potions is a part of many series, but is usually not the focus, so too is being a healer. Both I Shall Survive Using Potions and The Great Cleric follows main characters doing these lesser focused on activities as their main activity.
While I Shall Survive Using Potions isn’t only about using potions medicinally, it is a big part of the series. The Great Cleric focuses on a healer as the main character who wishes to help people in a world where healers charge exorbitant prices for healing and people die because of it. Both series feature main characters trying to change the system with their skills, but The Great Cleric is focused on him leveling up his magic and not being immediately overpowered.
For Fans of Cute, Fluffy Fantasy
Kuma Kuma Kuma Bear
Yuna much prefers staying home and playing her favorite VRMMO instead of going to school.
During an update, she receives a strange and powerful bear outfit. It was overpowered, but too embarrassing to wear in-game.
However, she finds herself suddenly transported to the world of the game, and her bear suit becomes her best chance of surviving.
While Kuma Kuma Kuma Bear is VRMMO-themed, it actually shares quite a lot with I Shall Survive Using Potions.
Both I Shall Survive Using Potions and Kuma Kuma Kuma Bear are female-led fantasy anime with a stylized cute art style about a main character with a unique perk that makes them OP in many situations. However, while those main characters are nice enough to most people, they are not naive with innocence like some anime girls. They use cunning, they know what they want from life, and they remain independent in their adventures due to their strength.
In short, Kuma Kuma Kuma Bear may have more action, and Yuna may wear a bear suit, but she has the same attitude as Kaoru.
Bofuri – I Don’t Want to Get Hurt, so I’ll Max Out My Defense
After receiving an invitation from a friend, Kaede Honjou starts playing the VRMMO game New World Online as a character named Maple.
However, in her desire to not get hurt, she puts all her stats in Vitality. This makes her move very slowly, unable to use magic, and get attacked by even the smallest creatures. However, it does allow her impenetrable defense, and the gear she finds while wandering grants her a one-hit counter skill.
And so, her adventures begin.
A strong and independent female main character doesn’t need to be mean, and both Bofuri and I Shall Survive Using Potions prove just that.
Both Bofuri and I Shall Survive Using Potions follow relatively pleasant female main characters who also aren’t pushovers. They go on their adventures, shut down people who are jerks, and enjoy their time in their fantasy world. However, while I Shall Survive Using Potions is an isekai, Bofuri is just about a girl playing a VRMMO.
It does merit being said that Bofuri is a lot more focused on action than anything else. It has softer, slice of life time, but the anime is about playing an MMO and much of playing an MMO is battling it out with things or people.
Do you have more anime recommendations like I Shall Survive Using Potions? Let fans know in the comments section below.
