When Kotarou Kawaii was in elementary school, he did a slime experiment like many other kids. However, the slime he made proved to be extraordinary when it came to life! While his slime, who he named Puniru, was a beloved friend, seven years later, her welcome has started to wear thin.
Now having transformed herself into a cute girl, Puniru accompanies Kotarou to middle school to throw lives into chaos.
Puniru really is a cute slime, and maybe a bit of a degenerate. If you are looking for more anime recommendations like Puniru is a Cute Slime, head on down below.
Anime Like Puniru is a Cute Slime
For Fans of Plagued By a Human-Like Non-Human
My Deer Friend Nokotan
After a youth spent as a violent delinquent, Koshi Torako reformed herself in her high school debut and has since fostered a pristine reputation as an honor student. However, her picturesque high school life comes to a screeching halt one day when she finds a girl with inexplicable deer horns tangled in the power lines.
Originally hoping to just pretend she never saw her, she meets the girl again in her class. It seems the odd deer girl Shikanoko Noko has now set her sights on Koshi and intends to make her a dear friend.
Similarities Between Puniru is a Cute Slime and My Deer Friend Nokotan
- Main character that just want s a normal school life is besieged by a strange girl obsessed with them.
- Meme-able absurd comedy and 4th wall-breaking jokes.
- Focuses on very specific things (slime, deer)
Differences Between Puniru is a Cute Slime and My Deer Friend Nokotan
- While it never leaves its absurd comedy behind, My Deer Friend Nokotan does become more formulated like a Cute Girls Doing Cute Things anime as it goes on. Puniru and its mixed-gender cast is more just comedic general school life.
- The comedy in Puniru is a Cute Slime is often very youthful and not quite as obviously degenerate as is it in My Deer Friend Nokotan.
Squid Girl
Terror of the seas Ika Musume has come out of the ocean to punish humanity for polluting her waters. With her ink-spitting skills and tentacles for hair, she is all set for invading Earth, but she didn’t count on two sisters bullying her into working at their seafood restaurant.
Similarities Between Puniru is a Cute Slime and Squid Girl
- Human characters have their life invaded by small, cute non-humans with big attitudes
- Absurd, silly comedy anime that can be sneaky degenerate at times.
- Non-human is occasionally the punching bag for comedy, but still maintains a sassy attitude.
- Non-humans can do unique things with their body
Differences Between Puniru is a Cute Slime and Squid Girl
- Squid Girl features the non-human as more of the main character whereas Kotarou is very much the main character of Puniru is a Cute Slime.
- The humans in Squid Girl are a lot more mean to the titular deity, though she deserves it.
- Squid Girl is more a “workplace comedy” compared to Puniru is a Cute Slime and its school-based comedy.
Urusei Yatsura
For skirt-chasing Ataru Moroboshi, the only notable thing about him is his extraordinary bad luck.
That luck kicks in when aliens suddenly invade Earth and he is chosen to represent humanity with their planet on the line. The duel for the fate of their planet ends up being a game of tag against the alien chief’s daughter, Lum.
While she is difficult to catch, eventually Ataru prevails by stealing her bikini top for the win.
However, his bad luck is at work again when Lum mistakes Ataru’s promise to marry his childhood friend as a proposal to her, which she has energetically accepted.
Similarities Between Puniru is a Cute Slime and Urusei Yatsura
- Human boy is plagued with the obsessive affection of a non-human girl
- Human boy’s romantic prospects for another girl are frequently dashed by the non-human obsessively affection for them.
- Often episodic comedy that can go any number of bizarre ways
Differences Between Puniru is a Cute Slime and Urusei Yatsura
- Puniru is a Cute Slime has a romantic element, but Urusei Yatsura is far more focused on developing its romance.
- Puniru is a Cute Slime often feels like comedy for a younger audience with sneaky adult jokes wedged in there, Urusei Yatsura is far more mature and more obvious with its mature/sexual jokes.
- Urusei Yatsura is about a romance between a human and an alien, so you see a lot more aliens pop up throughout the series.
- The male main character in Urusei Yatsura is an unrepentant womanizer, and has far more skill at it than Kotarou.
Drop Kick on My Devil
The demon Jashin was summoned to Earth by an occult dabbler named Yurine. However, although Yurine successfully summoned her, she doesn’t know how to send her back.
Now, Jashin ends up living with Yurine as her familiar. She knows the only way to go back now is to kill Yurine, but Jashin, incompetent as she is, can’t seem have any schemes go right.
Similarities Between Puniru is a Cute Slime and Drop Kick on My Devil
- Human lives with and is frequently pestered by a non-human that they created/summoned
- Episodic, slice of life comedy based in absurdity
Differences Between Puniru is a Cute Slime and Drop Kick on My Devil
- Dropkick on My Devil is less about slime girls, and more about various supernatural creatures
- Dropkick on My Devil uses extreme violence against the non-human (since they always come back to life) as comedy. It can be quite graphic.
- The human in Dropkick on My Devil is less expressive and more actively mean to the non-human as part of the comedy.
- Dropkick on My Devil has Cute Girls Doing Cute Things style comedy in that there isn’t a man to be found in it. Though Cute Girls Doing Violent Things is more fitting.
The Vampire Dies in No Time
Vampire hunter Ronald has received a job to rescue the son of a woman from the castle of what is said to be a legendarily powerful vampire.
However, upon arriving, he finds that this “powerful” vampire named Draluc immediately turned to ash when he kicked in the door. In fact, most things scatter him into a pile of ash as this “legendarily powerful vampire” is just strange reputation given to him. He’s actually super weak to everything.
Furthermore, the child in question was just freeloading there to play games during the day when Draluc was asleep and unaware.
In a strange turn of events, Draluc’s castle is destroyed and he and his armadillo move in with Ronald at his office. Now the pair work together taking care of the vampires and other problems that plague the city.
Similarities Between Puniru is a Cute Slime and The Vampire Dies in No Time
- Human is pestered by the non-human they live with for comedy
- Episodic comedy based on absurd, unexpected situations.
- The main duo is contentious, but still often nice to each other
- Features an occasional more adult joke, but most all-ages comedy
Differences Between Puniru is a Cute Slime and The Vampire Dies in No Time
- The Vampire Dies in No Time is more a supernatural comedy that follows a vampire hunter that took pity on a vampire that dies extremely easily.
- The Vampire Dies in No Time is far more diverse and unexpected with its comedy since it follows adults rather than children confined to a school.
Seton Academy – Join the Pack
Thanks to population decline, there are fewer humans left. Enter Mazama Jin, an animal hater who has enrolled in Seton Academy that is mostly anthropomorphic animal people.
He immediately falls in love the Hino Hitomi, the only other human female in class. Unfortunately, as he tries to become closer with her, he gets pulled into the various shenanigans of his classmates.
Similarities Between Puniru is a Cute Slime and Seton Academy
- Human boy is pestered mercilessly by a non-human girl that clearly likes him
- Human boy has a crush on another “normal” girl who is actually a little abnormal in what she likes.
- Episodic school life comedy where each new day is a new silly adventure
Differences Between Puniru is a Cute Slime and Seton Academy
- Puniru is a Cute Slime is slime and robots, Seton Academy is kemonomimi/anime people.
- Seton Academy is far more obviously a romance, and is a little less absurd with its comedy.
- The male main character in Seton Academy is a bit more mean to his non-human, at least at first.
For Fans of Absurd Slice of Lice
Azumanga Daioh
Chiyo Mihama is the strangest girl in her high school class of some already strange people. As a child prodigy, she skipped all the way to high school where she forms a bond with some of the oddest girls around.
Similarities Between Puniru is a Cute Slime and Azumanga Daioh
- Increasingly bizarre and absurd things happen to seemingly normal school children
- Episodic school comedies where unhinged situations arise
Differences Between Puniru is a Cute Slime and Azumanga Daioh
- Azumanga Daioh has no specific hook like the slime in Puniru is a Cute Slime provides, though it also doesn’t limit its comedy to realism either.
- Azumanga Daioh has a larger, all-female cast
- Puniru is a Cute Slime has a narrative structure for each episode, Azumanga Daioh is far more of a gag comedy in which there really isn’t any sort of plot driving any one episode most of the time.
Nichijou
Nichijou is about the daily lives of a trio of three friends who soon find their fate intertwined with a young genius, her robot maid, and talking cat. Needless to say, the normal does not ensue.
Similarities Between Puniru is a Cute Slime and Nichijou
- Doughy looking characters in school where increasingly weird things happen
- Episodic school life absurd comedy
Differences Between Puniru is a Cute Slime and Nichijou
- Nichijou follows three female main characters rather just one boy and his slime
- Nichijou, as it doesn’t have the same “slime hook” to it, is far more random with its comedy
The Great Jahy Will Not Be Defeated!
Feared and respected by her subjects, Jahy was second-in-command of the demon realm. However, one day, a magical girl attacks and destroys the mystic gem, and with it, the demon realm.
Flung into the human world, Jahy finds her powers greatly diminished, forcing her into a child’s form. While she can briefly return to her old form with a shard of the mystic gem, she now has to deal with real problems like paying rent and affording food all while trying to find the rest of the pieces of the shattered gem.
Similarities Between Puniru is a Cute Slime and The Great Jahy Will Not Be Defeated
- Small feisty non-human girl is constantly bullied by humans for comedy
- Episodic slice of life comedy where each new day brings new craziness
- Non-humans with an unearned sense of superiority for comedy
Differences Between Puniru is a Cute Slime and The Great Jahy Will Not Be Defeated
- The Great Jahy Will Not Be Defeated is about a demon general being sent to our world without much of her great power, then having to be chronically broke.
- The non-human is the main character in The Great Jahy Will Not Be Defeated, and she has no human that she is obsessed with like Puniru and Kotarou.
- The comedy in The Great Jahy Will Not Be Defeated is more about adult suffering when you are broke and underemployed.
Aho Girl
Yoshiko Hanabatake is an idiot. So much so that even her own mother has given up hope on her.
However, her studious and terrifying childhood friend A-kun is up to the task of shutting down her shenanigans at every turn.
Similarities Between Puniru is a Cute Slime and Aho Girl
- Normal teenaged boy is plagued by the obsessive attentions of a girl
- Girl is affectionate, clingy, and none too bright
- Episodic comedy about the various weird ways the girl derails the male main character’s peaceful life
Differences Between Puniru is a Cute Slime and Aho Girl
- Aho Girl features far more obvious sexual comedy (though it is not an ‘ecchi comedy,’ it just uses sex jokes on occasion)
- The male main character in Aho Girl is actively more mean to his female companion, though she is oblivious to it.
- Aho Girl is really just about an incredibly dumb girl. It is otherwise completely steeped in realisim. So no slime experiments coming to life or robot idol mascots.
Do you have more anime recommendations like Puniru is a Cute Slime? Let fans know in the comments section below.